Gabriel Nuñez earned his M.D. degree from the University of Seville, Spain, in 1977. He received postdoctoral training in Immunology at the University of
Texas Southwestern Medical Center, Dallas and residency training in
Anatomical Pathology at Washington University in St Louis. In 1987, he joined the laboratory of Stanley Korsmeyer at Washington University, where he
studied the function of the anti-apoptotic protein BCL-2. In 1991, he joined
the Department of Pathology at the University of Michigan in Ann Arbor as an Assistant Professor and was promoted to full Professor in 2001. He holds the Paul de Kruif Endowed Professorship in Academic Pathology. His laboratory
identified NOD1 and NOD2, the first members of the Nod-like receptor (NLR) family, a class of pattern-recognition receptors that mediate cytosolic sensing of microbial organisms. Nuñez and colleagues showed that genetic variation
in a NLR family member, NOD2, is strongly associated with susceptibility to
Crohn’s disease. Dr. Nuñez is the author of more than 380 scientific
publications that have resulted in more than 110,000 citations (h-index 155,
Google Scholar). He is an elected member of the National Academy of
Medicine.