副反応の低減したmRNA-LNPワクチンの開発Modulating Immunogenicity and Reactogenicity in mRNA-Lipid Nanoparticle Vaccines through Lipid Component Optimization

腹膜転移型胃がんに治療効果を示すmRNAワクチンを開発Neoantigen mRNA vaccines induce progenitor‑exhausted T cells that support anti‑PD‑1 therapy in gastric cancer with peritoneal metastasis

腸内細菌叢の乱れにより炎症性腸疾患が発症・重症化するメカニズムを明らかにOTUD3 prevents ulcerative colitis by inhibiting microbiota-mediated STING activation

COVID-19パンデミックが小学生の認知・非認知スキルに与えた影響Impact of COVID-19 pandemic on the cognitive and non-cognitive skills of elementary school students

⺟体の⼝腔環境と⼦どもの腸内健康が関連していることを発⾒Transmission of maternal oral pathobionts to the infant gut predisposes offspring to exacerbated enteritis

SARS-CoV-2の進化的動態：ヘパラン硫酸利用を介した感染戦略の解明Evolutionary dynamics of heparan sulfate utilization by SARS-CoV-2

病状の指標となる液性因子に応じて薬効タンパク質の産生量を自動調整する次世代mRNA医薬を開発Extracellular ligand-responsive translational regulation of synthetic mRNAs using engineered receptors

免疫vsマラリア原虫 攻防の鍵を握るタンパク質RIFINの機能を解明、ワクチン開発にも期待RIFINs displayed on malaria-infected erythrocytes bind KIR2DL1 and KIR2DS1

大腸菌の“触手”を原子レベルで解明！病原菌の付着メカニズムに迫るHigh-resolution cryo-EM analysis visualizes hydrated type I and IV pilus structures from enterotoxigenic Escherichia coli

PM_2.5が引き起こす呼吸器障害メカニズムを解明Aldehyde metabolism governs resilience of mucociliary clearance to air pollution exposure