腸内細菌叢の乱れにより炎症性腸疾患が発症・重症化するメカニズムを明らかにOTUD3 prevents ulcerative colitis by inhibiting microbiota-mediated STING activation
竹田潔教授、伊勢渉教授、菊池章特任教授、奥﨑大介特任准教授らの研究グループの研究成果が公開されました。
Title
OTUD3 prevents ulcerative colitis by inhibiting microbiota-mediated STING activation
Authors
Bo Li, Taiki Sakaguchi, Haruka Tani, Takayoshi Ito, Mari Murakami, Ryu Okumura,
Masao Kobayashi, Daisuke Okuzaki, Daisuke Motooka, Hiroki Ikeuchi,
Takayuki Ogino, Tsunekazu Mizushima, Seiichi Hirota, Yuriko Otake-Kasamoto,
Toshihiro Kishikawa, Shota Nakamura, Kouji Kobiyama, Ken J. Ishii,
Takao Hashiguchi, Taro Kawai, Etsushi Kuroda, Shinichiro Shinzaki, Wataru Ise,
Tomohiro Kurosaki, Akira Kikuchi, Yoshihiko Tomofuji, Yukinori Okada,
Kiyoshi Takeda, Hisako Kayama
Journal
Published online in Science Immunology on July 18, 2025
DOI
